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EXHIBITION AREA 

15.10-15.40
Coffee Break 

AUDITORIUM 

SESSION III – PROGNOSIS, MONITORING AND TREATMENT OF PATIENTS WITH LIVER DISEASE
Chairs: D. Alvaro, G. Germani 

15.40-15.55
AI in medical decision making: predictive models of disease progression and survival
G. Cirrincione 

15.55-16.10
Wearable and Digital Sensing in real time care
Q. Lai 

16.10-16.25
AI driven digital twinning: from drug development to personalization of care
D. Caligiore 

16.25-16.40
AI and liver transplantation: unravelling complexity
P. Burra 

16.40-17.05
Discussion 

SESSION IV – TALKING WITH AI IN THE HEPATOLOGY WARDS
Chairs: S. Gitto, G. Marrone 

17.05-17.20
The Opportunity and Pitfalls of Large Language Models in Hepatology
M. Giuffrè 

17.20-17.35
Hands-on session demonstrating practical applications of LLM in hepatology
F.A. Causio 

17.35-18.10
Discussion and Closing remarks
AISF Governing Board 

18.10-18.20
GENERAL ASSEMBLY 1
AISF Governing Board

PININFARINA

18.25-19.25
THE VALUE OF SHORT THERAPY IN PATIENTS WITH HCV AND COMORBIDITIES
Chair: Antonio Gasbarrini (Roma)
In-hospital screening and multi-disciplinary approach
Francesco Paolo Russo (Padova)
The 8-week therapy in the management of difficult to reach patients
Ivana Maida (Sassari)

ROOM A

08.00-09.00
MANAGEMENT OF MASLD
Chairs: L. Abenavoli, M. Masarone

AUDITORIUM

09.00-09.15
WELCOME & INTRODUCTION
AISF Governing Board 

09.15-10.15
GENERAL SESSION 1
Chairs: E.G. Giannini, F.P. Russo
Terminology, diagnosis and management of primary biliary cholangitis -autoimmune hepatitis variant syndrome (PBC-AIH): results from an international Delphi consensus process
Presenter: A. Gerussi (Monza)
Abstract Authors: A. Gerussi, M. Sebode, E. Nofit, A. Stoelinga, D. Bernasconi, A. Leburgue, P. Invernizzi, C. Schramm, B. Van Hoek, D. Tiniakos, L. Terracciano, M. Carbone, A. Lohse on behalf of the ERN RARE-LIVER, Global PBC Study Group and International Autoimmune Hepatitis Group – Monza, Hamburg (Germany), Leiden (The Netherlands), Paris (France), Newcastle upon Tyne (UK), Athens (Greece), Pieve Emanuele (MI), Rozzano (MI), Milan
Metabolic and Functional Characterization of CD8+ T-Cell Subpopulations in Hepatocellular Carcinoma: Implications of Tumor Microenvironment on T-Cell Dysfunction
Presenter: A. Montali (Parma)
Abstract Authors: A. Montali, V. Reverberi, A. Pelagatti, A. Vecchi, M. Rossi, S. Doselli, B. Farina, A. Olivani, G. Economopoulos, R. Dalla Valle, P. Fisicaro, C. Boni, G. Missale – Parma
Exploring the impact of mitochondrial biomarkers on HCC risk according to etiologic drivers: a multicenter study
Presenter: M. Longo (Milan)
Abstract Authors: M. Longo, A. Cespiati, E. Paolini, M. Meroni, D. Smith, A. Alisi, L. Miele, A. Dalbeni, R. Lombardi, G. Soardo, A.L. Fracanzani, P. Dongiovanni
Milan, Rome, Verona, Udine
Coronary angiography in liver transplant work-up: report from a large multicenter Italian cohort
Presenter: M. Saracco (Turin)
Abstract Authors: M. Saracco, P. Burra, V. Giannelli, G. Marrone, M.C. Morelli, D. Pagano, F.R. Ponziani, G. Svegliati Baroni, P. Toniutto, M. Biolato, S. Cariati, F. D’Arcangelo, N. De Maria, C. Di Benedetto, F.M. Donato, S. Fagiuoli, A. Ferrarese, E. Fumolo, A. Galeota Lanza, I. Lenci, L. Mameli, B. Magro, S. Marenco, L. Pasulo, M. Rendina, R. Viganò, M.V. Picciaiola, S. Martini – Turin, Padua, Rome, Bologna, Palermo, Ancona, Udine, Genoa, Modena, Milan, Bergamo, Verona, Naples, Cagliari, Bari
Role of spleen stiffness measurement by vibration-controlled transient elastography at 100Hz in guiding invasive hemodynamic reassessments after underdilated TIPS
Presenter: D. Saltini (Modena)
Abstract Authors: D. Saltini, T. Guasconi, C. Caporali, M. Bianchini, F. Casari, F. Prampolini, B. Lei, M. Scoppettuolo, F. Ascari, A.S. Velasco Mayorga, A. Piscopo, A. Colecchia, F. Schepis – Modena 

10.15-10.45
STATE OF THE ART LECTURE
Recompensation in cirrhosis: patient discharge or change of paradigma?
Thomas Reiberger
Presenter: P. Caraceni 

EXHIBITION AREA 

10.45-11.15
Coffee Break 

AUDITORIUM 

11.15-12.15
SYMPOSIUM I
ADVANCES IN AUTOIMMUNE LIVER DISEASE 
Chairs: P. Invernizzi, C. Rigamonti
First-Line Therapy in AIH: comparing AZA and MMF
N. Cazzagon
Second line therapy for PBC: evaluating efficacy in Real-world and Clinical Trial Settings
U. Vespasiani Gentilucci
Drivers of Disease Progression in Primary Sclerosing Cholangitis:Implications for Risk Assessment
M. Carbone 

12.15-12.30
PREMIO ALLA CARRIERA PROF. PAOLO ANGELI
Presenter: P. Burra 

12.30-13.00
POLICY, PUBLIC HEALTH ANDADVOCACY NETWORK
AISF Governing Board, Antonello Aurigemma (Presidente del Consiglio regionale del Lazio), Ivan Gardini (Presidente EpaC), Referente intergruppo parlamentare Epatiti virali e Malattie di fegato

EXHIBITION AREA

13.00-14.00
Lunch & poster view 

ROOM GH 

14.00-15.00
CPT SYMPOSIUM (No E.C.M.)
CHALLENGING ISSUES IN LIVER TRANSPLANTATION TODAY
Chairs: V. Giannelli, S. Martini, D. Pagano
Introduction of the symposium
P. Toniutto
Physical, psychosocial, economic issues
D. Dondossola
Patients over 70 years old
M.C. Morelli
Patients with use of illicit substances
M. Di Nicola
Discussion
Discussants: G. Marrone, F.R. Ponziani, G. Svegliati Baroni
Conclusions of the day
P. Burra 

SALA DELL’ARCHITETTURA + SALA DELL’EDITORIA 

14.00-15.00
ULTRASOUND LAB (No E.C.M. – Under 30)
N. De Matthaeis, M. Fraquelli, G. Galati, D. Roccarina 

ROOM GH 

15.00-15.50
PARALLEL SESSION 1 (No E.C.M.)
Chairs: S. Fagiuoli, A. Federico
Feasibility and effectiveness of liver transplantation following immunotherapy in patients with hepatocellular carcinoma
Presenter: G. Amaddeo (Créteil, France)
Abstract Authors: G. Amaddeo, M. Allaire, M.S. Franzè, C. Dupré, S. Caruso, T. Antonini, Y. Chouik, H. Regnault, A. Beaufrère, J. Ursic-Bedoya, M. Ningarhari, T. Uguen, A. Jaillais, O. Roux, L. Blaise, R. Gerolami, A. Pascale, R. Brustia, D. Sommacale, J. Dumortier, V. Leroy – Créteil (France), Paris (France), Lyon (France), Clichy (France), Montpellier (France), Lille (France), Rennes (France), Tours (France), Bobigny (France), Marseille (France), Villejuif (France)
One-year changes in alt and lsm, not in cap, predict long-term liver outcomes in patients with metabolic dysfunction-associated steatotic liver disease
Presenter: G. Pennisi (Palermo)
Abstract Authors: G. Pennisi, G. Infantino, G. Di Maria, E. Tsochatzis, E. Bugianesi, M. Yoneda, M.H. Zheng, H. Hagström, J. Boursier, J.L. Calleja, G. Boon-Bee Goh, W.K. Chan, R. Gallego-Durán, A.J. Sanyal, V. de Lédinghen, P.N. Newsome, J.G. Fan, L. Castéra, M. Lai, C. Fournier-Poizat, G. Lai-Hung Wong, A. Armandi, A. Nakajima, W.Y. Liu, Y. Shang, M. de Saint-Loup, E. Llop, K.K. Jun Teh, C. Lara-Romero, A. Asgharpour, S. Mahgoub, M.S.W. Chan, M. Romero-Gomez, H. Lin, S.U. Kim, T. Cheuk-Fung Yip, A. Tulone, J. Che-To Lai, B. Yang, H.W. Lee, G. Ciancimino, M. Enea, C. Cammà, V.W.S. Wong, S. Petta – Palermo, London (UK), Turin, Yokohama (Japan), Wenzhou (China), Stockholm (Sweden), Angers (France), Madrid (Spain), Singapore, Kuala Lumpur (Malaysia), Seville (Spain), Richmond (USA), Paris (France), Shanghai (China), Clichy (France), Boston (USA), Hong Kong (China), Birmingham (UK), Seoul (Korea, Rep. of South)
The early dynamic changes of radiological and biochemical scores help identify a more aggressive PSC phenotype
Presenter: E. Catanzaro (Padua)
Abstract Authors: E. Catanzaro, M. Peviani, E. Bonaiuto, F. Pezzato, M. Benatti, M. Gambato, P. Burra, R. Motta, N. Cazzagon – Padua
MASLD and FIB4 are independent predictors of major adverse liver outcomes and cardiovascular events in type 2 diabetes: findings from a single-center cohort using AI-driven machine learnin
Presenter: A. Liguori (Rome)
Abstract Authors: V. Calvez, C. Dachena, L. Petrucci, A.R. Barberio, L. Antenucci, C. Masciocchi, A. Liguori, A. Sciarra, L. Tartaglione, S. Paternello, A. Gasbarrini, D. Pitocco, L. Miele – Rome

PININFARINA 

15.00-15.50
PARALLEL SESSION 2 (No E.C.M.)
Chairs: E. Claar, M. Rendina
The early impact of bariatric surgery on liver fibrosis and steatosis in MASLD patients
Presenter: V. Cossiga (Rome)
Abstract Authors: V. Cossiga, M. Capasso, S. Albano, V. Schiavone, L. Ranieri, F. Capozzi, A. Franzese, M. Guarino, M. Musella, F. Morisco – Naples
HDV persistence acts independently from HBV reservoir extent and is sustained by HBsAg production mainly derived from integrated HBV-DNA
Presenter: S. D’Anna (Rome)
Abstract Authors: S. D’Anna, L. Piermatteo, G. Brancaccio, E. Teti, A. Di Lorenzo, I. Grossi, G. Torre, V. Malagnino, M. Iannetta, F. Ceccherini-Silberstein, C. Pasquazzi, U. Cillo, A. Vitale, E. Gringeri, M. Magrofuoco, M. Pacenti, L. Baiocchi, S. Francioso, I. Lenci, A. Koffas, A.M. Geretti, M.L. Abate, A. Olivero, G.B. Gaeta, L. Sarmati, M. Rizzetto, U. Gill, P. Kennedy, G.P. Caviglia, V. Svicher, R. Salpini – Rome, Padua, London (UK), Turin, Naples
Expert-Validated Framework for Large Language Models in HCV Care: A Comparative Analysis of RAG and Fine-Tuning Using Clinical Guidelines
Presenter: M. Giuffrè (New Haven, USA)
Abstract Authors: M. Giuffrè*, N. Pugliese*, S. Kresevic, M. Ajcevic, F. Negro, M. Puoti, X. Forns, J.M. Pawlotsky, D.L. Shung†, A. Aghemo – ***Junior co-authorship, **Senior co-authorship – New Haven (USA), Pieve Emanuele (MI), Rozzano (MI), Trieste, Geneva (Switzerland), Milan, Barcelona (Spain), Madrid (Spain), Créteil (France), Paris (France)
Changes in body mass composition do not predict post-transplant outcome in cirrhosis patients with hepatocellular carcinoma undergoing liver transplantation
Presenter: F. D’Arcangelo (Padua)
Abstract Authors: F. D’Arcangelo, M. Marchiori, J. Lanari, A. Ferrarese, M. Gambato, S. Piano, G. Germani, F. P. Russo, M. Senzolo, P. Angeli, U. Cillo, P. Burra, A. Zanetto – Padua

AUDITORIUM

15.50-16.05
GENERAL ASSEMBLY 2 (No E.C.M.)
AISF Governing Board 

16.05-17.05
SYMPOSIUM II
PROGRESS AND CHALLENGES IN VIRAL HEPATITIS 
Chairs: R. Bruno, A. Craxì
Challanges and opportunities in the path towards HCV elimination
A. Aghemo
Future treatment for HBV: how might we achieve functional cure
P. Lampertico
HDV Management: expert approaches to screening and treatment
M.R. Brunetto 

17.05-18.05
GENERAL SESSION 2
Chairs: S. Montagnese, F. Schepis
Trends in complications and mortality among individuals with chronic liver disease and cirrhosis: a population-based cohort study
Presenter: F.P. Russo (Padua)
Abstract Authors: F.P. Russo, A. Zanetto, L. Salmaso, C. Barbiellini Amidei, S. Battistella, S. Piano, P. Angeli, P. Burra, M. Saia, U. Fedeli – Padua
Influence of the MBOAT7 rs641738 polymorphism on the prognosis of patients with metabolic dysfunction-associated steatotic liver disease and hepatocellular carcinoma
Presenter: M. Guariglia (Turin)
Abstract Authors: M. Guariglia, G.P. Caviglia, C. Rosso, S. Gaia, E. Rolle, M.L. Abate, A. Armandi, P. Carucci, E. Bugianesi – Turin, Mainz (Germany)
Effect of Protease-Activated Receptor 2 inhibition by 1-Piperidinepropionic acid in lipid accumulation, inflammation and hepatocellular carcinoma development
Presenter: P. Guerra (Padua)
Abstract Authors: P. Guerra, G. Villano, C.M. Rejano-Gordillo, M. Ruvoletto, A. Biasiolo, S. Quarta, P. Peña-SanFelix, S. De Siervi, S. Cagnin, C. Turato, M.L. Martínez-Chantar, P. Pontisso, A. Martini – Padua, Bizkaia (Spain), Pavia
Genome-wide association study of noninvasive scores of fibrotic MASLD in an Italian population
Presenter: F. Malvestiti (Milan)
Abstract Authors: F. Malvestiti, V. Moretti, S. Mira, O. Jamalamadi, S. Pelusi, G. Periti, L. Ronzon, L. Miano, M. Tranchina, C. Rosso, G. Pennisi, A. Armandi, A. Liguori, F. Terracciani, R. Perbellini, G. Soardo, A. Federico, U. Vespasiani Gentilucci, L. Miele, E. Bugianesi, R. D’Ambrosio, S. Petta, D. Prati, S. Romeo, L. Valenti – Milan, Gothenburg (Sweden), Turin, Palermo, Udine, Naples, Rome
Impact of sexual dimorphism on liver damage in patients with metabolic-dysfunction associated steatotic liver disease
Presenter: E. Dileo (Turin)
Abstract Authors: E. Dileo, C. Rosso, M. Parasiliti-Caprino, G.P. Caviglia, F. Ponzetto, L. Leoni, G. Pennisi, A. Armandi, M. Guariglia, F. Saba, M. Maccario, S. Petta, G. Mengozzi, E. Bugianesi – Turin, Palermo 

PININFARINA

18.10-19.40 
TRANFORMING PATIENT’S LIVES IN LIVER DISEASES
Welcome and Introduction 
Silvia Bencivelli (Roma) 
Transforming Patients’ Lives in PBC: a sight on the evolution of PBC care 
M. Marzioni (Ancona) 
Transforming Patients’ Lives in HCV: Progress in hepatitis C Management 
A. Mangia (San Giovanni Rotondo, FG) 
Transforming Patient’s Lives in HDV: pioneering innovation transforming patient journey 
P. Lampertico (Milano) 
Closing Remarks 
Silvia Bencivelli (Roma) 

ROOM A

08.00-09.00
MANAGEMENT OF PATIENTS WITH SUCCESSFULLY TREATED VIRAL HEPATITIS
Chairs: G. Brancaccio, E. Degasperi

AUDITORIUM

09.00-10.00
GENERAL SESSION 3
Chairs: A. Gasbarrini, M. Persico
Burden of Hepatitis D Virus infection in Italy: final results from the HDV Describe study
Presenter: G.P. Caviglia (Turin)
Abstract Authors: G.P. Caviglia, A. Loglio, M. Viganò, S. Fagiuoli, P. Colombatto, B. Coco, E. Dileo, T. Manetta, A. Olivero, G. Troshina, A. Ciancio, D. Angrisani, G.G. Di Costanzo, C.F. Magni, S. Antinori, G. Rizzardini, V. Messina, M. Milella, A. Saracino, M. Quaranta, S. Taurian, C. Quarta, G. Cariti, V. Cossiga, F. Morisco, S. Cretella, G. Verucchi, E. Biliotti, A.R. Garbuglia, G. D’Offizi, R. Cotugno, M. Barone, R. Cozzolongo, E.M. Cela, E. Falbo, G.A. Niro, M. Feasi, E. Pontali, C. Coppola, R. Rapetti, M. Pirisi, N. Capoluongo, N. Cuomo, A. Perrella, A. Izzi, T.A. Santantonio, V. Di Marco, C. Cosentino, A. Marrone, M. Pisaturo, N. Coppola, G. Cologni, M. Rizzi, F. Barbaro, A.M. Cattelan, E. Fornasiere, P. Toniutto, M. Pallozzi, F.R. Ponziani, M. Dallio, M. Romeo, A. Federico, R. Viganò, L.S. Belli, L. Rapisarda, E. Siciliano, E. Bracciamà, A. Risicato, G. Bertino, M. Puoti, A. Civolani, M. Distefano, E. Teti, M. Andreoni, P. Anolli, P. Lampertico, G. Mengozzi, T. Stroffolini, M.R. Brunetto, M. Rizzetto – Turin, Bergamo, Milan, Pisa, Naples, Caserta, Bari, Bologna, Bologna, Rome, San Giovanni Rotondo (FG), Castellana Grotte (BA), Foggia, Lamezia Terme (CZ), Genoa, Gragnano (NA), Novara, Palermo, Padua, Udine, Milan, Catania, Cagliari, Siracusa
Duodenal organoids from patients with MASLD-cirrhosis display impaired mitochondrial energy metabolism and antioxidant defense
Presenter: F. Salomone (Catania)
Abstract Authors: F. Salomone*, A. Filippello*, S. Di Mauro, A. Scamporrino, A. Fichera, M. Licata, A.M. Amorini, S. Piro*Equal contribution
Catania, Enna, Catania
High burden of MASLD and metALD in People with HIV: a call for liver fibrosis screening prioritization
Presenter: F. Cinque (Montreal, Canada – Milan)
Abstract Authors: F. Cinque, J. Milic, R. Righetti, D. Kablawi, L. R. Ballesteros, W. Elgretli, M. Shengir, B. Lebouché, N. Kronfli, M.B. Klein, J. Bischoff, A.L. Fracanzani, A. Bandera, R. Lombardi, J.K. Rockstroh, G. Guaraldi, G. Sebastiani  – Montreal (Canada), Milan, Modena, Bonn (Germany)
Involvement of the ERG1 potassium channel in cholangiocarcinoma cell biology
Presenter: G. Alla Viligiardi (Florence)
Abstract Authors: G. Alla Viligiardi, J. Iorio, M. Pastore, C. Duranti, R. Colasurdo, C. Capitani, T. Lottini, A. Arcangeli, C. Raggi, F. Marra – Florence
Real-world practice patterns on the use of terlipressin in patients with cirrhosis and acute kidney injury – results from the ICA-GLOBAL AKI study
Presenter: S. Incicco (Padua)
Abstract Authors: S. Incicco, A. T. Ma, A. Juanola, K. Patidar, A. Barone, A. Kulkarni, J. L. Perez-Hernandez, B. Wentworth, S. Asrani, C. Alessandria, N. Abdelaaty Abdelkader, Y. J. Wong, Q. Xie, N.T. Pyrsopoulos, S.E. Kim, Y. Fouad, A. Torre, E. Cerda Reyes, J. Diaz-Ferrer, R. Maiwall, D. Simonetto, M. Papp, E. Orman, G. Perricone, C. Sole, C. M. Lange, A. Farias, G. Pereira, A. Gadano, P. Caraceni, T. Thevenot, N. Verma, J.H. Kim, J.D. Vorobioff, J. Cordova-Gallardo, V. Ivashkin, J. P. Roblero, R. Maan, C. Toledo, O. Riggio, E. Fassio, M. Marino, P. Nabilou, V. Vargas, M. Merli, L. Lofego Goncalves, L. Rabinowich, A. Krag, L. Balcar, P. Montes, A. Z. Mattos, T. Bruns, A. M. Nur, W. Laleman, E. Carrera Estupinan, M.C. Cabrera, M. Girala, H. Samant, S. Raevens, J. Madaleno, W.R. Kim, J.P. Arab, J. Presa, C. Noronha Ferreira, A. Galante, O. Roux, A. S. Allegretti, R.B. Takkenberg, S. Marciano, S.K. Sarin, P. Gines, P. Angeli, E. Sola, S. Piano – Padua, Toronto (Canada), Barcelona (Spain), Houston (USA), Hyderabad (India), Ciudad de Mexico (Mexico), Charlottesville (USA), Dallas (USA), Turin, Cairo (Egypt), Singapore, Shanghai (China), Newark (USA), Anyang (Korea, Rep. of South), Minia (Egypt), Lima (Peru), New Delhi (India), Rochester (USA), Debrecen (Hungary), Indianapolis (USA), Milan, Barcelona (Spain), Munich (Germany), Sao Paulo (Brazil), Rio de Janeiro (Brazil), Buenos Aires (Argentina), Bologna, Besancon (France), Chandigarh (India), Seoul (Korea, Rep. of South), Rosario (Argentina), Tlalpan (Mexico), Moscow (Russian Federation), Santiago (Chile), Rotterdam (The Netherlands), Valdivia (Chile), Rome, Hvidovre (Denmark), Vitoria (Brazil), Tel Aviv (Israel), Tel Aviv (Israel), Odense (Denmark), Vienna (Austria), Bellavista (Peru), Porto Alegre (Brazil), Aachen (Germany), Addis Ababa (Ethiopia), Leuven (Belgium), Quito (Ecuador), Asuncion (Paraguay), New Orleans (USA), Ghent (Belgium), Coimbra (Portugal), Stanford (USA), Vila Real (Portugal), Lisboa (Portugal), Lugano (Switzerland), Clichy (France), Boston (USA), Amsterdam (The Netherlands) 

10.00-10.30
STATE OF THE ART LECTURE TRANSITION FROM PEDIATRIC TO ADULT CARE IN LIVER DISEASES: CHALLENGES AND EXPECTATIONS
L. D’Antiga
Presenter: A. Grieco 

10.30-10.40
BEST PAPER BASIC (No E.C.M.)
T. Pollicino, L. Valenti
BEST PAPER CLINICAL
G. Svegliati Baroni, A. Vitale 

EXHIBITION AREA 

10.40-11.10
Coffee Break 

ROOM GH 

11.10-12.10
PARALLEL SESSION 3 (No E.C.M.)
Chairs: V. Di Marco, M. Senzolo
Non-invasive follow-up of cardiac hemodynamics after trans-jugular intrahepatic portosystemic shunt: focus  on left ventricular global longitudinal strain
Presenter: R. Stupia (Desenzano del Garda, BS)
Abstract Authors: R. Stupia, M. Bevilacqua, S. Romano, F. Cattazzo, L. De Marco, D. Sacerdoti  – Desenzano del Garda (BS), Verona, Belluno
Thrombus generation under flow conditions in patients with cirrhosis and thrombocytopenia: the CirTAS-study
Presenter: N. Bitto (Milan)
Abstract Authors: N. Bitto, G. Tosetti, A. Tripodi, A. Lecchi, S. La Marca, L. Padovan, E. Scalambrino, M. Clerici, C. Caputo, A.L. Fracanzani, M. Primignani, P. Lampertico, F. Peyvandi, V. La Mura – Milan
Prognostic role of endoscopic ultrasound guided direct portal pressure gradient measurement in porto-sinusoidal vascular disorder
Presenter: L. Giuli (Rome)
Abstract Authors: L. Giuli, G. Rizzatti, M. Pallozzi, F.R. Ponziani, B. E. Annicchiarico, G. Tripodi, A. Contegiacomo, A. Posa, R. Iezzi, R. Talerico, A. Gasbarrini, A. Larghi, F. Santopaolo – Rome
Unravelling MASLD heterogeneity at single cell level in the switching towards progressive disease
Presenter: M. Meroni (Milan)
Abstract Authors: M. Meroni, E. Paolini, M. Longo, M. Battistin, E. Mosca, P. Pelucchi, A. Chiodi, A. Sula, S. Gatti, P. Dongiovanni – Milan
Systemic oxidative stress correlates with sarcopenia and pruritus severity: two independent relationships simultaneously burdening the quality of life in patients with Primary Biliary Cholangitis
Presenter: M. Dallio (Naples)
Abstract Authors: M. Dallio, M. Romeo, F. Di Nardo, C. Napolitano, P. Vaia, A. Coppola, L. Ventriglia, A. Silvestrin, C. Basile, A. Federico – Naples

PININFARINA 

11.10-12.10
PARALLEL SESSION 4 (No E.C.M.)
Chairs: F. Morisco, M. Viganò
Bulevirtide for patients with chronic Hepatitis D (CHD) in Italy: a multicenter prospective nationwide real-life study (D-Shield)
Presenter: M.P. Anolli (Milan)
Abstract Authors: M.P. Anolli, E. Degasperi, G. D’Offizi, A. Rianda, A. Loglio, M. Viganò, A. Ciancio, Y. Troshina, M.R. Brunetto, B. Coco, S. Zaltron, L. Turco, L. Sarmati, M. Milella, P. Toniutto, L. Marinaro, F.P. Russo, A. Gori, I. Maida, A. Federico, T.A. Santantonio, E.G. Giannini, G. Verucchi, F. Morisco, A. Mangia, S. De Nicola, B. Pinchera, M. Maracci, A. Romano, S.L. Crocè, P. Gatti†, R. Zampino, M. Persico, P. Pozzoni, A. Pan, A. Pellicelli, N. Coppola, F. Pileri, M. Tonnini, A. Soria, M. Puoti, P. Lampertico – Milan, Rome, Bergamo, Turin, Pisa, Brescia, Bologna, Bari, Udine, Padua, Sassari, Naples, Foggia, Genoa, San Giovanni Rotondo (FG), Rozzano (MI), Ancona, Trieste, Brindisi, Baronissi (SA), Lecco, Cremona, Modena, Monza
Oncostatin M modulates the biology of cholangiocarcinoma cells and the tumor microenvironment
Presenter: N. Porro (Florence)
Abstract Authors: N. Porro, J. Nurcis, S. De Siervi, M. Cadamuro, C. Turato, S. Mantovani, B. Oliviero, L. Fabris, M. Mondelli, F. Marra, M. Parola, A. Caligiuri, M. Pastore, S. Cannito, A. Gentilini – Florence, Turin, Padua, Pavia
Investigating Notch3 expression in hepatocellular carcinoma and its interplay with KDM2A
Presenter: I. De Giorgi (Florence)
Abstract Authors: I. De Giorgi, T. Caruso, M.C. Scavuzzo, S. Piaggi, F. Scolari, P. Faviana, S. Pillozzi, R. Del Frate, G. Paties Montagner, F. Bartoli, A. Corti, G. Cavallini, V. Carloni, L. Gragnani – Florence, Pisa
Characterization of the intrahepatic immune microenvironment in a large cohort of patients with untreated hepatitis B virus infection
Presenter: M.S. Franzè (Créteil, France)
Abstract Authors: M.S. Franzè, P. Maille, S. Caruso, J. Calderaro, Y. Bouda, A. Sessa, S. Chevaliez, P. Ingiliz, T. Pollicino, G. Raimondo, J.M. Pawlotsky, V. Leroy, G. Amaddeo – Créteil (France), Messina
Fibrates in Primary Sclerosing Cholangitis: a multicenter retrospective observational study
Presenter: L. Cristoferi (Monza)
Abstract Authors: L. Cristoferi, A. Curto, M. Maxwell, L.K. Lund, E. Nofit, D. Bernasconi, D. D’Amato, O. Falco, M. Scaravaglio, F. Malinverno, A. Gerussi, P. Invernizzi, E. Culver, C. Schramm, D. Assis, M. Carbone – Monza, Florence, Connecticut (USA), Hamburg (Germany), Oxford (UK), Milan 

AUDOTORIUM

12.10-13.10
SYMPOSIUM III
LIVER ONCOLOGY 
Chairs: S. Bhoori, F. Piscaglia
Advancements in HCC Systemic Therapies: evaluating safety and effectiveness
G. Cabibbo
New paradigms in the treatment of unresectable colorectal liver metastasis
U. Cillo
Evolving concepts and therapeutic approaches for iCCA and pCCA
M. Marzioni

SALA DELL’ARCHITETTURA + SALA DELL’EDITORIA 

13.10-14.10
ULTRASOUND LAB (No E.C.M. – Under 30)
N. De Matthaeis, M. Fraquelli, G. Galati, D. Roccarina 

EXHIBITION AREA 

13.10-14.10
Lunch & poster view 

AUDITORIUM 

14.10-14.55
GENERAL ASSEMBLY 3 (No E.C.M.)
AISF Governing Board 

14.55-15.55
SYMPOSIUM IV
MASLD & MetALD 
Chairs: A.L. Francanzani, F. Marra
Interplay between metabolic dysfunction and alcohol on the progression of liver disease
S. Petta
Setting up an appropriate referral for high risk patients
E. Bugianesi
Will emerging therapies for MASLD change the natural history of the disease?
L. Miele 

15.55-16.10
GENERAL ASSEMBLY 4 (No E.C.M.)
AISF Governing Board 

16.10-16.15
2 PREMI BEST ORAL (No E.C.M.)
2 PREMI BEST POSTERS (No E.C.M.)
Clinical
V. Giannelli, R. Sacco
Basic
C. Saitta, F. Salomone 

16.15-16.30
CLOSING REMARKS
AISF Governing Board